From Aerospace & Automotive to In-Silico Medicine, with Roger Assaker

The entrepreneurial journey using Computational Modeling & Simulation (CM&S) and Artificial Intelligence (AI) to address customer needs


This webinar of the VPHi Keynote Webinar Series featuring Roger Assaker, co-founder and CEO of the start-up MDSim, took place on Monday 2 October 2023 at 4pm CEST live at the Universitat Pompeu Fabra and broadcasted on Zoom.

You can rewatch it on YouTube


The talk covers the entrepreneurial journey using innovative Computer Modeling & Simulations (CM&S) technology and Artificial Intelligence (AI) to solve a market need and create value. This journey will be illustrated by 2 cases:

  • e-Xstream engineering - where we took advanced research on multi-scale material modeling from the university and developed it - Technology & Business - to become the leader in advanced material modeling technology used by the top Fortune 500 Industrial customers all around the world
  • MDsim - a cross-industry innovation using Computer Modeling & Simulation (CM&S) and Artificial Intelligence (AI) to improve the quality of life of millions of patients suffering from spine degeneration and deformity

The talk will cover the technology stack (high-level) but also the business and other, less-tangible, items used during this journey. We will end-up by highlighting the similarity and differences between the use of CM&S in the industry (Aero, Auto, …) and in Medicine (i.e. In-Silico Medicine).


Roger Assaker got his PhD in the civil engineering from University Catholique de Louvain (1998). He is currently the chief executive officer in MDSIM company, Luxembourg. MDSIM is a health-tech start-up active in the in-silico medicine. The company is focused on using computer modeling and simulation (CM&S) combined to data sciences and AI to help improving the quality of life of millions of patients around the globe. The company is developing Software as a Medical Device (SaMD) aimed at helping medical device companies and surgeons to develop and use optimal medical solutions for a better patient care. Roger is also a technology entrepreneur and a passionate for customer engagement and people leadership. He tackles challenging problems using innovative technology and business models. He co-founded e-Xstream engineer in 2003 and he grew it to become the world leader in ICME before selling it to MSC Software in 2012. He Joined MSC as Chief Material Strategist while continuing to be the CEO for e-Xstream engineering.

This webinar is organised within the VPHi keynote webinar series, a quarterly event organized by the VPHi Young Scientists Committee that provides a forum for access to senior community members and their expert competence for chiefly young scientists, but also to the VPH community as a whole.

With the series, VPHi wishes to:

  • Offer added value to prospective young scientists through core content
  • Create visibility of VPH knowledge dissemination for external stakeholders
  • Highlight excellence within the VPHi, additionally providing student members with a label of quality
  • Promote scientific interaction between junior and senior community members and across VPHi disciplines



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