• Verifying and Validating Quantitative Systems Pharmacology and In Silico Models in Drug Development: Current Needs, Gaps, and Challenges

    This commentary paper published in "CPT: Pharmacometrics & Systems Pharmacology" reports the outcome of a multistakeholder workshop on the validation challenges for in silico models in drug development. The event was organized on 25 - 26 April 2019 in (Leuven) Belgium in collaboration with the VPH Institute.
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  • Avicenna Roadmap: "in silico Clinical Trials: How Computer Simulation will Transform the Biomedical Industry"

    The ultimate aim of the Avicenna support action was to create a research and technological development Roadmap outlining a strategy for in silico Clinical Trials (ISCT). As project partner, VPHi contributed to the development of this important document that over 11 chapters describes the route by which in silico techniques of computer simulation will be introduced into clinical trials, the studies that are routinely conducted to establish the safety and efficacy of new medical interventions.
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  • White Paper on Big Data: "Big data, big knowledge - big data for personalised healthcare"

    On Oct 2014, a White Paper on "Big Data for Personalized Healthcare" is presented to the European Commission. The paper is edited by Marco Viceconti, Peter Hunter, Keith McCormack, Adriano Henney, Stig W. Omholt, Norbert Graf, Edwin Morley-Fletcher, Liesbet Geris, and Rod Hose.
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  • Response to petition requesting ban on all animal experiments in Europe

    On Jan 31st, 2014 the VPH Institute releases a second position statement on this topic, which proposes computer simulation as the best option to reduce, refine and partially replace animal testing in scientific research.
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  • Joint statement on in silico medicine research in Europe

    Presented during the networking session hosted by the VPH Institute at the ICT 2013 conference (6-8 Novermber, 2013 Vilnius), this document exposes the vision of the VPH community on the role of in silico medicine as one of the priorities of H2020. 
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  • Digital Patient roadmap

    The Digital Patient Roadmap is a comprehensive document currently being written for the European Commission that sets out a research agenda for the realisation of the Digital Patient. The responsibility for the delivery of this roadmap was given to the DISCIPULUS project, funded by the EC under the Seventh Framework Programme (FP7/2007-2013).
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  • Position Paper on Data Protection Regulation

    The Institute wrote a formal position statement to fully support the amendments to the LIBE Committee Report on the Data Protection Regulation, which adequately take into account the needs of public health researchers. This statement -in the form of an email- was sent to all relevant MEPs.
    Download - VPHI Position Paper on Data Protection Regulation (0.29 MB)

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  • Pharma 2020: The vision - Which path will you take?

    This report produced by PricewaterhouseCoopers in June 2007is the first in the series. It indicates that the current pharmaceutical industry business model is both economically unsustainable and operationally incapable of acting quickly enough to produce the types of innovative treatments demanded by global markets. In order to make the most of these future growth opportunities, the industry must fundamentally change the way it operates.
    Download - Pharma 2020: The vision: which path will you take? (0.69 MB)

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  • Seeding the EuroPhysiome

    A Roadmap to the Virtual Physiological Human, produced by the STEP consortium in 2007.
    Download - STEP Roadmap: "Seeding the EuroPhysiome" (3.12 MB)

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  • VPH White Paper

    Titled "Towards Virtual Physiological Human: multilevel modelling and simulation of the human anatomy and physiology", this white paper was edited by DG INFSO & DG JRC in November 2005
    Download - VPH White Paper (0.52 MB)

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