Application closing date: 15 October 2017.
The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations world-wide. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Barcelona (Spain), Grenoble (France), Hamburg (Germany), Hinxton near Cambridge (UK) and Rome (Italy).
Questions about tissues and organs (development, regeneration, homeostasis, cancer) are still most often tackled at the molecular or cellular level. New technical advances such as organoid culture, 3D mesoscopic imaging, multicellular transcriptomics and computer modelling are helping us to go beyond the molecular and cellular level, to understand multicellular feedback loops, long-range signalling networks and emergent collective decisions, and thus to see tissues and organs as systems in their own right. Modelling these higher-level processes in vitro and in silico will help us understand: what goes wrong in diseased and cancerous tissues, how organs can regenerate, and how to engineer new tissues.
EMBL Barcelona will focus on going beyond the molecular and cellular scale, integrating gene circuits with a tissue-level quantitative understanding of organs, both healthy and diseased. To this end EMBL will forge collaborations with the excellent local research hospitals in Barcelona.
EMBL now seeks 2 outstanding candidates for junior group leader positions to start some time after February 2018. They should present an inspiring plan for a systems biology approach to studying biology at the multicellular level, in any of the following areas: organoids, hiPSC disease modelling, tissue homeostasis, development, regeneration, cancer, immunology, vasculogenesis, tissue engineering, microfluidics technology, bio-printing, and organ-on-a-chip technology.
EMBL believes strongly in an interdisciplinary approach, combining experimental biology with computational modelling, engineering or biophysics. Proposals are encouraged to take advantage of our mesoscopic imaging facility which provides cutting-edge technologies for digitizing organoids, tissues and embryos in 3D and 4D. Researchers will also have access to state-of-the-art facilities for genomics, proteomics, FACS and high-powered microscopy.
More details about these positions can be found here