PhD and postdoc opportunities - January 2024

Postdoctoral position in Biomedical Engineering with a focus on Artificial Intelligence for Additive Manufacturing
Uppsala University

BioMaterial Systems (BmS) is a research group in the Division of Biomedical Engineering at the Department of Materials Science and Engineering at Uppsala University. The focus of the group is on the use of additive manufacturing (AM, or 3D-printing) to develop new biomaterials and implant designs.

Project description: Additive manufacturing, or 3D-printing, is a disruptive technology enabling the manufacturing of complex structures as well as new material combinations and tailored material microstructures. However, process parameter development to enable printing of new materials with the desired properties may be extremely costly, time- and material consuming. This project will focus on the use of advanced statistical models and machine learning for the additive manufacturing process. The methods will be applied to experimental data derived from powder bed fusion with laser beam (PBF-LB) of biodegradable alloys (Mg- and Zn-based), as these are particularly challenging to process and the microstructures achieved can be very complex. These alloys are promising biomaterials for bone-healing implants due to their ability to be replaced by bone tissue while degrading within the human body.

Deadline: 7 February 2024

More info and application HERE

Researchers "normal class" (CRCN) and Inria Starting Faculty Positions (ISFP)

• Inria centre at the University of Bordeaux

The Inria Centre at the University of Bordeaux, in line with its site policy with the University of Bordeaux and the University of Pau and the Pays de l'Adour, gives priority to recruitment in the ASTRAL, CONCACE and GEOSTAT project-teams. The center also wishes to give priority to recruitment in newly-created project-teams or those in the process of being created. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria Center at Grenoble Alpes University

The Inria Centre at Grenoble Alpes University, in line with its site policy, has made it a priority to strengthen the following themes: environment and responsible computing; data and knowledge management; software-hardware interface; digital health. The center also wishes to give priority to recruitment in newly-created project teams or those in the process of being created. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria Center at the University of Lille.

The Inria Centre at the University of Lille, in line with its site policy, has set itself the priority of strengthening the following areas in which it wishes to develop: cybersecurity (networks, distributed systems, software engineering), in conjunction with the Campus Cyber Hauts-de-France Lille Métropole; responsible digital technologies (energy efficiency, digital sobriety, reduction of environmental impact), in the most inclusive sense of the major fields of digital research. The center also wishes to give priority to recruitment in newly-created project teams or those in the process of being created. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria Lyon Centre

In line with its site policy, the Inria Lyon Center's priority is to strengthen the following themes: digital technology for life sciences and medicine; distributed robotics. The center also wishes to give priority to recruitment in newly-created project-teams or those in the process of being created. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria Centre at the University of Lorraine

The Inria Centre at the University of Lorraine, including the Inria branch at the University of Strasbourg, in line with its site policy with the University of Lorraine and the University of Strasbourg, wishes to give priority to profiles with a strong orientation towards (1) software or hardware development, (2) healthcare and (3) engineering (including industry 4.0). The center also wishes to give priority to recruiting from newly-created project teams or those in the process of being created. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria Paris Centre

The Inria Centre Paris, in line with its site policy with its partner universities, in particular within the Inria Centre of Sorbonne University, has three recruitment priorities: artificial intelligence (learning, optimization, automatic language processing, vision); interfaces between digital sciences and life sciences or health; networks and systems. The center also wishes to give priority to recruiting from newly-created project teams or those in the process of being created. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria centre at the University of Rennes

The Inria Centre at the University of Rennes, in line with its site policy with its partner universities, wishes this year to recruit as a priority in its new or renewing teams: ARTISHAU, CIDRE (SUSHI / PIRAT), ERMINE, LINKMEDIA, MYRIADS, SUMO, on the following themes: AI security, security at the hardware/software interface, understanding cyber-attacks, supervision and resilience of information systems, network economics, security of artificial intelligence algorithms, frugality of edge-fog-cloud infrastructures, verification of distributed systems. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria Centre of the University Cote d'Azur

The Centre Inria d'Université Côte d'Azur, including the Inria Antenna at the University of Montpellier, in conjunction with its partner universities, is looking to recruit for the COMPO and PREMEDICAL project-teams, with particular emphasis on profiles in the following fields: (1) robotics, (2) algorithmic differentiation, (3) geometry and (4) artificial intelligence. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

• Inria Centre in Saclay

In conjunction with its partners, Université Paris Saclay and Institut Polytechnique de Paris, the Inria Saclay center focuses on the following priorities: interfaces between digital and life sciences, interfaces between digital and social sciences, privacy, operating systems. The center also wishes to give priority to recruitment in newly-created project teams or those in the process of being created. More generally, the recruitment campaign is broadly open to all the research themes of the center's teams.

Deadline to apply: February 6, 2024

More info and application HERE

________________________________________________________________

3 PhD positions Space toxicology, In vitro toxicology, Experimental hepatology/pharmacology
Department of Pharmaceutical and Pharmacological Sciences at VUB-Belgium - Prof Mathieu Vinken

1) innovative research project focused on studying the effects of altered gravity on cellular communication in liver in vitro and in vivo

2) innovative research project focused on producing and testing new drug candidates for the treatment of inflammatory liver disease

3) innovative research project focused on testing a novel approach based on in vitro technology and artificial intelligence to study chemical-induced liver toxicity

Deadline for application: 15 February 2024

More info HERE

________________________________________________________________

2 Research Associates in Multiphysics-Informed ML for Cardiovascular Modelling
The University of Manchester, UK

We are seeking to appoint two ambitious and proactive Research Associates to be part of a multidisciplinary team developing high-fidelity models of cardiovascular fluid dynamics and device-flow/device-tissue interactions through multi-physics and physiological modelling. The candidates will leverage clinical and experimental data, first-principle physics-based simulations, scientific machine-learning approaches, data assimilation, and uncertainty quantification techniques. Integral to this work will also be the application of these techniques to large real-world multimodal datasets, clinical trials datasets and population imaging studies.

Requirements:

• PhD in computational cardiovascular mechanics and prosthetic valves or related fields
• expertise in either computational solid mechanics to analyse soft-tissue deformations and device interactions or computational fluid mechanics to enable analysis of haemodynamics and thrombosis
• experience in working with multiphysics and multiscale models and in accelerated methods for solving partial differential equations and scientific machine learning (physics-informed machine learning) is essential
• a developing publication profile will be advantageous

Closing date: 19/02/2024

More info and application HERE

________________________________________________________________

PhD Position in Clinical Simulations for Brain Aneurysm Treatment
Faculty of Science - University of Amsterdam

The Computational Science Lab at the University of Amsterdam invites applications for a PhD Research Position, centering on the development and validation of simulation tools aimed at revolutionizing planning strategies for clinical interventions, particularly focusing on the non-invasive treatment of brain aneurysms. This position situates within a vibrant research group that maintains a broad scientific collaboration network, including several clinical institutes, experimental groups, and supercomputing centers across Europe.

Project: Simulating Clinical Interventions in Brain Aneurysm Treatment

Aim: Develop and validate high-fidelity simulation tools designed to optimize planning, prediction, and decision-making processes related to clinical interventions in treating brain aneurysms, utilizing in-depth in silico solutions within the framework of the Virtual Human Twin.

Tasks and key responsibilities:

• Developing a simulation tool that assists in planning and predicting various treatment scenarios for brain aneurysms;
• Validating the simulation and applying uncertainty quantification to enhance fidelity and enable patient-specific utilization;
• Applying and combining methodologies from computational fluid dynamics, solid mechanics, and mathematical optimization;
• Collaborating with both local and international partners (this includes clinical, experimental, and computational partners) to maintain the comprehensiveness and applicability of the research;
• Participate in education, based on mutual agreement (assisting in one of our courses or supervising student thesis projects).

Closing date: 29 February 2024

More info and application HERE

10 PhD positions in the Europe Horizon Marie Skłodowska-Curie Project REBONE

REBONE is about to open 10 fully funded PhD positions to construct a platform of computational tools that will enable clinical experts to produce customized bone graft substitutes for the treatment of critical-size bone defects. This innovation will ensure that an ideal treatment solution is found on a patient-specific basis in terms of:

• mechanical and mechano-biological performance,
• surgical implantability, and
• manufacturing process reliability

List of available PhD positions:

• Methods for optimization of bone-substitute architectures (Politecnico di Milano, Italy);
• Micro- and macro-mechanical characterization of materials and devices and in-silico Models (Politecnico di Milano, Italy);
• 3D printing technologies for Glass-Ceramic and Glass-Ceramic-based composite BTE scaffolds (Politecnico di Torino, Italy);
• Tissue-scaffold biological interaction (Università del Piemonte Orientale, Italy)
• Design of bone inspired scaffolds and biomechanical characterization of the bone-scaffold construct (Université de Liege, Belgium)
• Industrial process for glass-ceramic device manufacturing through VPP (Lithoz GmbH, Austria)
• Characterization of fracture relevant bone sites for information on the structural/compositional requirements of the implant (Ludwig Boltzmann Institute, Austria)
• Models for Tissue growth and fundamental relationships with micro-architecture of scaffolds (University of Salzburg, Austria)
• Biomimetic in vitro culture models for evaluation of novel bone substitute implants (University of Belgrade, RS)
• Mixed reality for planning of implant surgery for bone defects of irregular shapes (MEDAPP SPÓŁKA AKCYJNA, Poland)

Deadline for online application: 01/03/2024

More info and application HERE

________________________________________________________________

Computational Design and Performance Simulation of Bioabsorbable Metallic EMD
Universidad Politecnica de Madrid, Madrid, Spain - IMDEA Materials, Madrid, Spain - Meotec GmbH, Aachen, Germany

The project will develop a computational optimization framework to identify the optimum parameters for candidate stent designs (e.g., number, size, and shape of struts, surface treatments) to tailor the temporally evolving load-bearing capacities of devices. Numerical tools will be used to predict short-term performance and this will be coupled with a physicallybased phase-field framework to account for surface corrosion.

The objectives of this project are:

1. Develop an in silico finite element framework to enable virtual bench testing of stent structures through prediction of functional properties, such as crimp, deployment, recoil, foreshortening, radial strength and bending.

2. Implement a surface-based corrosion model through phase-field modelling to enable prediction of spatial and temporal progression of corrosion of stent structures that will enable quantification of how mechanical properties evolve over time (e.g. virtual corrosion testing).

3. Validate the developed framework against the experimental results provided by DC5.

More info and application, see DC6 HERE