In a recent press release the EC officially speaks about the “great achievements” of the EU-US integrating research project on in silico oncology: CHIC
"The novelty created by the large scale transatlantic CHIC project refers to a host of aspects of fundamental science, biomedical technology and future clinical medicine related to the quantitative understanding of cancer and the patient individualized treatment optimization of the disease", states the EC article.
The EU funded CHIC (Computational Horizons in Cancer) project aimed at advancing ISM through the paradigm of ISO in the following aspects:
In the CHIC Consortium, 17 leading organizations from Europe and the USA share their expertise in clinical research and care, multiscale cancer modeling, multi-level data analysis, semantic interoperability and data protection. Highly innovative cancer hypermodels collaboratively developed by the consortium cancer modellers have provided, among other things, the framework and the testbed for the development of the CHIC technologies. The following four paradigmatic cancer types have been addressed:
Treatment with a variety of therapeutic modalities including chemotherapy, radiation therapy, immunotherapy and hormone therapy has been considered and simulated.
The project results
The actual components developed by CHIC include
Multiscale models and data are semantically annotated using the developed ontological and annotating tools. An image processing and visualization toolkit, and cloud and virtualization services have also been developed. The CHIC tools, services, infrastructure and repositories can provide the community with a collaborative interface for exchanging knowledge and sharing work in an effective way. A number of developed features and tools enhance usability and accessibility.
An exemplary key novel characteristic of CHIC has been the large scale intercontinental cancer multimodeller hypermodelling strategy supported by cutting edge software engineering technologies. The latter enable the technologically facilitated semi-automatic creation of new patient-centred cancer hypermodels by reusing pre-existing simpler component models and combining them in several scientifically and clinically plausible ways. CHIC has exploited to the fullest the great potential of geographically distributed world leading research teams active in the fields of multiscale cancer modelling, biomedical informatics technologies and clinical medicine.
To read the full article please visit the EC website
More information on the project can be found on the CHIC final newsletter