Wellcome Leap's Dynamic Resilience program, jointly funded with Temasek Trust, seeks breakthroughs that will enable more resilience as we age.
Wellcome Leap and Temasek Trust have partnered to launch a US$60 million (~S$80 million) Dynamic Resilience programme aimed at increasing health spans. Average human life expectancy has doubled from 35 to 70 years over the past century, but health spans have not correspondingly improved. Data shows that worldwide, more than 1 in 2 adults aged over 60 have multimorbidity, or multiple co-existing health issues. This and decreasing dynamic resilience - the ability to respond to and cope with stress - contribute to clinical frailty which makes us vulnerable to sudden and serious health deterioration in the event of acute illness or injury.
Multimorbidity poses an urgent challenge for health services and this is set to increase in the coming decades. Frailty affects up to half of adults over 65 globally, and people who have experienced traumatic injury, cancer treatment, or menopause. Frailty reduces our ability to live independently and increases the likelihood of falls, hospitalization, the need for long-term care, and death. The negative impact of frailty and age-related ill health on patients, their families, caregivers, and societies, is unsustainable.
The Dynamic Resilience programme aims to reduce frailty progression by 25% which could prevent 71,000 hospitalizations and 8,000 deaths annually from falls in the US alone and benefit 87 million older adults globally.
The three program goals are:
Full information on the call can be found here