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DOCUMENTS

2015

  • Avicenna Roadmap: "in silico Clinical Trials: How Computer Simulation will Transform the Biomedical Industry"

    The ultimate aim of the Avicenna support action was to create a research and technological development Roadmap outlining a strategy for in silico Clinical Trials (ISCT). As project partner, VPHi contributed to the development of this important document that over 11 chapters describes the route by which in silico techniques of computer simulation will be introduced into clinical trials, the studies that are routinely conducted to establish the safety and efficacy of new medical interventions.
    External link

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2014

  • White Paper on Big Data: "Big data, big knowledge - big data for personalised healthcare"

    On Oct 2014, a White Paper on "Big Data for Personalized Healthcare" is presented to the European Commission. The paper is edited by Marco Viceconti, Peter Hunter, Keith McCormack, Adriano Henney, Stig W. Omholt, Norbert Graf, Edwin Morley-Fletcher, Liesbet Geris, and Rod Hose.
    External link

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  • Response to petition requesting ban on all animal experiments in Europe

    On Jan 31st, 2014 the VPH Institute releases a second position statement on this topic, which proposes computer simulation as the best option to reduce, refine and partially replace animal testing in scientific research.
    External link

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2013

  • Joint statement on in silico medicine research in Europe

    Presented during the networking session hosted by the VPH Institute at the ICT 2013 conference (6-8 Novermber, 2013 Vilnius), this document exposes the vision of the VPH community on the role of in silico medicine as one of the priorities of H2020. 
    External link

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  • Digital Patient roadmap

    The Digital Patient Roadmap is a comprehensive document currently being written for the European Commission that sets out a research agenda for the realisation of the Digital Patient. The responsibility for the delivery of this roadmap was given to the DISCIPULUS project, funded by the EC under the Seventh Framework Programme (FP7/2007-2013).
    External link

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  • Position Paper on Data Protection Regulation

    The Institute wrote a formal position statement to fully support the amendments to the LIBE Committee Report on the Data Protection Regulation, which adequately take into account the needs of public health researchers. This statement -in the form of an email- was sent to all relevant MEPs.

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2012

  • Consultation on directions for Future and Emerging Technologies (FET) research

    In November 2012, the VPH Institute contributed to the public consultation on directions for Future and Emerging Technologies (FET) research, highlighting the potential of the VPH technology. 
    External link

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  • WHITE PAPER: "VPH, Molecular Systems Biology (MSB), and their ITFoM"

    Produced by the ITFoM (Future of Medicine) consortium, this paper describes the contribution of VPH and MSB to the ITFoM vision and the collaboration between the two founding streams.

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  • Report on VPH International Activities (2011-12)

    Father of the IUPS Physiome Project and very active in the VPH initiative since the very beginning, Prof. Peter Hunter has invested a great amount of energy this year in the international activities related to the VPH Institute.This document contains all the details.  

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  • Proceedings of the 2012 5th International Advanced Research Workshop on In Silico Oncology and Cancer Investigation – The TUMOR Project Workshop (IARWISOCI)

    This is an open access version of the proceedings of the conference. The conference was technically co-sponsored by IEEE-EMBS and funded by the European Commission through the Transatlantic TUMOR Project in the Framework of the Virtual Physiological Human (VPH) Initiative.

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  • Position Statement on the open letter “Why we need a new strategy for health research in Europe”

    The Policy Affaris Work Group of the VPH Institute produced a position statement to express its support to the motion recently published by the Standing Committee of the European Medical Research Councils (EMRC) of the European Science Foundation (ESF), entitled “Why we need a new strategy for health research in Europe

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  • Position Statement on animal experimentation

    The Policy Affaris Work Group of the VPH Institute produced a position statement on the animal experimentation topic, supporting the thesis that the principles of virtual modelling technologies provided by the VPH can be applied to animal experimentation and help reducing the number of animals used.

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  • Discipulus Roadmap: First Draft

    This is the first draft of the Digital Patient Roadmap, based on 1st Consultation meeting (Barcelona, March 30th, 2012) and early results. 

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  • Integrating knowledge representation and quantitative modelling in physiology

    Full reference: De Bono, B. and Hunter, P.J. Integrating knowledge representation and quantitative modelling in physiology. Biotechnol. J. 7:958–972, 2012. DOI 10.1002/biot.201100304
    External link

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2011

  • VPH-FET Research Roadmap

    "Advanced Technologies for the Future of the Virtual Physiological Human", Editors: Marco Viceconti, Gordon Clapworthy – September 2011.

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  • GREEN PAPER: "From Challenges to Opportunities: Towards a Common Strategic Framework for EU Research and Innovation funding"

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  • ARGOS Position Paper

    This is the position paper written by the ARGOS consortium, the the Transatlantic Observatory for Meeting Global Health Policy Challenges through ICT-Enabled Solutions. The document emerged from the consensus discussion organised by the VPH community in Europe and the MSM/IMAG community in USA. 

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  • ARGOS Policy Brief

    This is the Policy Brief on the establishment of a joint VPH Cyber infrastructure between Europe and United States, elaborated by the ARGOS transatlantic observatory in 2011.

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2009

  • Virtual Tissues - a quantum leap in biomedical research

    This position paper presents the outcome of the First International Workshop on Virtual Tissues: v-Tissues 2009, which was held in April 21-22, 2009, at the EPA Campus in Research Triangle Park, NC, USA.
    External link

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  • The impact of modeling on Biomedical Research

    This is the final report produced by the Interagency Modeling and Analysis Group (IMAG) as a result of the IMAG Futures Meeting held on December 15-16, 2009 in Bethesda -Maryland. 

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  • "A Vision and Strategy for the VPH in 2010 and beyond"

    This document written by the VPH NoE (Network of Excellence) consortium supplements the original STEP Research Roadmap with the vision for the next 5-10 years.

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2008

  • Pharma 2020: Virtual R&D - Which path will you take?

    This is the second paper in the PwC Pharma 2020 series. Produced in in June 2008 it explores how pharma companies could dramatically improve the R&D productivity. 

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2007

  • Pharma 2020: The vision - Which path will you take?

    This report produced by PricewaterhouseCoopers in June 2007is the first in the series. It indicates that the current pharmaceutical industry business model is both economically unsustainable and operationally incapable of acting quickly enough to produce the types of innovative treatments demanded by global markets. In order to make the most of these future growth opportunities, the industry must fundamentally change the way it operates.

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  • Seeding the EuroPhysiome

    A Roadmap to the Virtual Physiological Human, produced by the STEP consortium in 2007.

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2005

  • VPH White Paper

    Titled "Towards Virtual Physiological Human: multilevel modelling and simulation of the human anatomy and physiology", this white paper was edited by DG INFSO & DG JRC in November 2005

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