New calls with deadlines end May-early June
Research Associate in Multiphysics-Informed ML for Cardiovascular Modelling
Division of Informatics, Imaging & Data Science - The University of Manchester
Applicants should have a PhD in computational cardiovascular mechanics and prosthetic valves or related fields and expertise in either computational solid mechanics to analyse soft-tissue deformations and device interactions or computational fluid mechanics to enable analysis of haemodynamics and thrombosis. One of the critical challenges we want to tackle is how to efficiently execute ensembles of virtual experiments entailing. Experience in working with multiphysics and multiscale models and in accelerated methods for solving partial differential equations and scientific machine learning (physics-informed machine learning) is essential. A developing publication profile will be advantageous.
Deadline for application: 8 May 2024
More info and application HERE
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Programme Manager Computational Medicine & Regulatory Science Portfolio
Department of Computer Science - The University of Manchester
The successful candidate will play a major role in developing and shaping the portfolio, working closely with the Director to grow the Centre and plan and deliver an exciting programme of activities, including leading key science translational activity and development of use cases in the Centreā€™s key domains, partnership development, bid writing, resource management, impact and public engagement strategies. You will have a strategic mindset and a track record of building and leading collaborative relationships and professional networks, expertise in a domain ideally related to medical image analysis and modelling with an emphasis on machine learning (phenomenological models) and computational physiology (mechanistic models) and, excellent communication and interpersonal skills, experience in managing high-performing teams, and demonstrable ability to support the preparation and management of large, complex grant proposals to take up the role of Programme Manager for the portfolio of grants under Prof Alejandro Frangi.
Deadline for application: 26 May 2024
More info and application HERE
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Phd Position in Multiscale Modelling of Endothelial Cell Monolayers in Health and Disease
Computational Science Lab, University of Amsterdam, Prof. Alfons Hoekstra
PhD position focusing on multiscale modelling of Endothelial Cell (EC) monolayers in the microvasculature, coupling molecular models of intracellular signalling to cell-level models of spatially resolved signalling, and finally to coupling many of such single cell-level models together in a multicellular EC monolayer. The goal is to study specific pathways (based on RhoA and RhoB GTPases) and their impact on EC monolayer integrity. You will study differential pathways that drive fast and transient (RhoA-mediated), or slow and persistent (RhoB-mediated) loss of endothelial integrity. You will merge in silico modelling with in-vitro experiments carried out in close collaboration with another PhD student in this joint project to address bistability and hysteresis in the differential RhoA/B-dependent control of microvascular leak. You will study cell-to-cell variability in responses to activating stimuli and address the switch from acute to chronic EC activation.
Application deadline: 10 June 2024
More info and application HERE
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PhD position Biomechanics of internal fixation methods for ankle fusion
University of Sheffield - Department of Mechanical Engineering
Ankle fusion is a common treatment for advanced ankle arthritis to relieve pain and improve functional outcomes. However, there is a reported non-union rate of 5-37%, requiring further surgery or an ankle replacement. Moreover, there are several options for internal fixation, with no consensus on the number of screws, orientations, and placement in ankle fusion surgery.
This project aims to develop validated computational models of the foot and ankle, and investigate the biomechanical parameters impacting successful bone healing while reducing the risk of fixation failure.
The project will involve parametric analysis of participantsā€™ data, finite element analysis and mechanical testing. Hence, the candidate will be consulting with collaborators in orthopaedic surgery, bioengineering, mechanical engineering and the Insigneo Institute. The candidate will gain a unique opportunity to carry out research in an exciting interdisciplinary project to answer important clinical questions.
Deadline for application: 18 June 2024
More info and application HERE
