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6 to 10 September 2021

2 nd International School on In Silico Trials

Five - afternoons intensive school, organized by VPHi - Virtual Physiological Human Institute with the support of the In Silico World Project, for decision-makers in medical industries, research hospitals, contract research organizations, regulatory agencies and notified bodies, from 6 to 10 September 2021, online on Teams.

2 nd International School on In Silico Trials In the past few years, it became possible, in some cases, to provide evidence of safety and efficacy for new medical products using modelling and simulation, what is now referred to as In Silico Trials.

This could be a game-changer, but it is also a disruptive innovation that may require some changes in the business model of many companies.

The 2nd International School on In Silico Trials will offer a systematic, non-specialist review on the strengths and the weakness of in silico trials technologies. The participants will be guided in the development of a better and deeper understanding of the threats and opportunities that this unprecedented technology presents, with the goal to enable more informed decision-making on the adoption of these innovations.

The school this year is organized by methods. After an introduction of the Director Prof. Marco Viceconti, a world-class expert will present a specific modelling method, illustrate it around a specific exemplar use case, and provide a critical review of the pros and cons of such method. We will lecture on molecular dynamics, systems biology, machine learning, computational fluid dynamics, finite element modelling, and agent-based modelling. We will also lecture on the use of high-performance computing, and the challenges posed by multiphysics and multiscale models. We will close with a systematic SWOT analysis of the adoption of In Silico Trials in the average biomedical company, and a review of the current regulatory landscape.

By engaging both researchers and industry in the conversation on how to roll out this roadmap, the Avicenna Alliance is the one stop shop for all things in silico medicine at EU level.

Full details to come soon.

Want more information? istschool@vph-institute.org

Program

Date / Time

Lecturer

Lecture

Monday, 6 September 2021

15:00 - 16:45

Marco Viceconti

What is a model? Introduction to In Silico Medicine

17:00 - 18:45

Andrea Beccari

Molecular dynamics models for drugs design

Tuesday, 7 September 2021

15:00 - 16:45

Liesbet Geris

Systems biology models for tissue engineering applications

17:00 - 18:45

Michela Milano

Machine learning: main methods, strengths and weaknesses

Wednesday, 8 September 2021

15:00 - 16:45

Rodney Hose

Computational Fluid Dynamics models for cardiovascular applications

17:00 - 18:45

Francesco Pappalardo

Agent-Based models of the immune system

Thursday, 9 September 2021

15:00 - 16:45

Marco Viceconti

High Performance Computing simulations to test bone drugs

17:00 - 18:45

Blanca Rodriguez

Multiscale models to evaluate cardiotoxicity

19:00 - 20:45

Peter Hunter

Multiphysics models for cardiac modelling

Friday, 10 September 2021

15:00 - 16:45

Enrico Dall'Ara

Finite Element models for anternatives to animal experimentation

17:00 - 18:45

Luca Emili

In Silico Trials: SWOT analysis to sell it to your boss

19:00 - 20:45

Prasanna Pathmanathan

In Silico Trials: the regulatory landscape

Download the program (.pdf)

Scholarship

For the 2021 edition of the International School on In Silico Trials, the organization committee will offer three scholarships for students regularly enrolled in universities from lower- income economies.

The scholarships will be assigned to the first three applicants who meet the requirements.

What does the scholarship include?

Each scholarship is worth €510 and includes the VPHi members subsidized fee to participate to the school, and the students’ fee for a one-year membership to the VPHi, that will grant access to all the resources, events and networking activities of the Institute.

Who can apply for a scholarship?

All students regularly enrolled in universities from low, lower-middle and upper-middle income economies according to the World Bank classification can apply.

Check if the country where your university is located is listed in the low, lower-middle and upper-middle income tables at this link:

https://datahelpdesk.worldbank.org/knowledgebase/articles/906519-world-bank-country-and-lending-groups

How to apply for a scholarship?

Send an email to istschool@vph-institute.org in which you describe your research project and why the International School on In Silico Trials is relevant for your project.

Don’t forget to include the Proof of Enrolment to the University.

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